gastric emptying — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2319	Acotiamide monohydrochloride trihydrate	Acotiamide hydrochloride,YM-443 HCl,Z-338 HCl	AChE
	Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamid...		AChE
T31597	Ecabapide	DQ2511,DQ 2511,DQ-2511	Others
	Ecabapide (DQ-2511) is a novel gastrointestinal motility promoter that significantly enhances gastric emptying in SHRSP.Ecabapide activates cyclic GMP-dependent housekeeping Cl- channels in rabbit gastric wall cells.		Others
T68100	Mifentidine	DA 4577	Histamine Receptor
	Mifentidine (DA 4577) is an orally available H2 receptor antagonist for the study of gastric emptying and experimental gastric and duodenal ulcers.		Histamine Receptor
T3727	Methyl syringate	Syringic Acid Methyl Ester	TRP/TRPV Channel
	Methyl syringate (Syringic Acid Methyl Ester) has a unique inhibitory activity toward aflatoxin production with a different mode of action from that of gallic acid. Methyl syringate from K. pictus is a specific and selec...		TRP/TRPV Channel
T5S1389	Escin IB		5-HT Receptor , NO Synthase
	Escin Ib inhibits gastric emptying, at least in part, mediated by capsaicin-sensitive sensory nerves, to stimulate the synthesis and/or release of dopamine, to act through central dopamine2 receptor, which in turn causes...		5-HT Receptor , NO Synthase
T1291	Cisapride	Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase	Potassium Channel , 5-HT Receptor , HER
	Cisapride (R 51619) is a serotonin type 4 (5-HT4) receptor agonists are potent prokinetic agents that act on serotonin receptors in the intestine and promote intestinal peristalsis, increase gastric emptying and decrease...		Potassium Channel , 5-HT Receptor , HER
T5S2360	Corydaline	Corydalin,(+)-Corydaline	P450 , Virus Protease , Opioid Receptor , AChE
	1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr...		P450 , Virus Protease , Opioid Receptor , AChE
T21385	Cinitapride	Paxapride,Cidine,cinitapride tartrate,Blaston,Cintapro,Cinmove	5-HT Receptor
	Cinitapride (Blaston) is a gastroprokinetic agent. It slows the actions of the muscles to reduce the symptoms of conditions such as acid reflux, delayed gastric emptying, and ulcer dyspepsia. Cinitapride acts as an antag...		5-HT Receptor
T34281	Relamorelin	BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131	GHSR
	Relamorelin (RM-131), a selective and potent growth hormone-releasing peptide/growth hormone secretagogue receptor (GHSR) agonist, is a potent growth hormone-releasing peptide mimetic with a high affinity for the GHS-1a ...		GHSR
T31214	Dazopride fumarate	AHR-5531C
	Dazopride fumarate is a peristaltic used to enhance gastric emptying and block emesis.
T27550	HMR-1426	HMR 1426,HMR1426
	HMR-1426 is gastric emptying inhibitor. HMR1426 shows an anorectic potential in rats and decreased body weight and fat mass. This was achieved solely by reducing food intake without influencing overall energy expenditure...
TP2095	Astressin 2B
	Potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist (IC50 values are 1.3 and > 500 nM for CRF2 and CRF1 respectively). Antagonizes CRF2-mediated inhibition of gastric emptying.
T76319	Urocortin III (mouse) (free acid)
	Urocortin III (mouse) (free acid), a selective agonist with high affinity for the CRF2 receptor, significantly inhibits gastric emptying while not affecting colonic transit [1] [2].
T63237	Acotiamide hydrochloride
	Acotiamide hydrochloride is a selective, orally active, reversible acetylcholine ester (AChE) inhibitor (IC50: 1.79 μM) that increases gastric contractility, accelerates delayed gastric emptying, and can be used to study...
T39236	Relamorelin acetate	Relamorelin acetate,RM-131 acetate,BIM-28131acetate
	Relamorelin (RM-131) acetate is a pentapeptide ghrelin analog that acts as a selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR). It exhibits a high affinity for the GHS-1a receptor, with a Ki v...
T68735	Ciclotropium (free base)
	Ciclotropium (free base) is quaternary ammonium compound with anticholinergic and parasympatholytic activity. Oral Cyclotropium bromide inhibited fasting and meal-stimulated colonic motility significantly without causing...
T76195	Stresscopin-related peptide (human)
	Stresscopin-related peptide (human), a specific ligand for the type 2 CRH receptor, effectively suppresses food intake, delays gastric emptying, and decreases heat-induced edema. It plays a crucial role in maintaining ho...
T81080	Strictinin
	Strictinin, a phenolic compound extracted from Pu'er teas, exhibits antiviral, antibacterial, and laxative properties. Its mode of action involves speeding up intestinal transit without promoting gastric emptying, boosti...
T83694	Gastric Inhibitory Peptide (1-42) (porcine) TFA	GIP (1-42),Glucose-dependent Insulinotropic Polypeptide (1-42)
	Gastric inhibitory peptide (GIP) (1-42), an endogenous incretin hormone comprising 42 amino acids, promotes insulin secretion. Expressed in the intestinal neuroendocrine K cells and submandibular gland, it enters circula...
T22230	Acotiamide
	Acotiamide is an orally active, selective and reversible acetylcholinesterase ( AChE ) inhibitor, with IC 50 of 1.79 μM. Acotiamide is a gastroprokinetic agent that enhances gastric contractility and accelerates delayed ...